At Flawless Trillion™ we have the answers at the fundamental cellular level.
PGD2 is Prostaglandin D2 and it is the pathway that Pharma researchers have discovered in balding scalp - Hair growth is also now understood to be not just about increasing hair growth mechanisms - it is also about reducing hair inhibiting mechanisms which is what PGD2 is.
Scientists are developing PGD2 inhibitors as the next big breakthrough to grow hair that is much better beyond minoxidil.
"Prostaglandin D2 (PGD2) levels are high in the balding areas of human scalps, and PGD2 has been found to inhibit hair growth. It is known that the inhibition of the PGD2 receptor can promote hair growth by preventing hair follicles from entering the catagen phase.
In this study, we identified that the DP2 antagonist (DP2A) could ameliorate alopecia in human follicle dermal papilla cells (HFDPCs) that were stimulated by dihydrotestosterone (DHT), a known molecule related to hair loss. We observed that the DP2A promoted wound healing efficiency and increased alkaline phosphatase levels in the HFDPCs that were damaged with DHT. In addition, we found that the DP2A diminished the reactive oxygen species (ROS) levels generated in the DHT-damaged HFDPCs. We confirmed that the DP2A effectively recovered the membrane potential of mitochondria in these cells."
Men and women both lose hair via Androgenic Alopecia because both men and women have the hormones that cause hair loss and the mechanisms inhibiting hair growth.
PGE2 is postulated to stimulate hair-follicle growth by improving the number of hair-follicle stem cells (HFSCs), such as – Sox9+ and Lgr5+ cells. Furthermore, the new hair follicles with gradually formed outer root sheath structures comprised more Sox9+.
We lower PGD2 and support PGE2 internally in your body with a patented Medical Food nutrition that is built on organic ingredients in superior ratios which are all key to making it work.
We have researched and discovered with doctor's clinical experience and PhD research support, that the type of fats that you have been eating and taking is actually lowering your hair's cellular energy and impairing the growth of your hair.
Now for the first time in history, you can repair the cells from the inside based on science, and watch your hair blossom like the Spring time.
Medications such as Minoxidil both topical and oral, raise levels of PGE2 which is a prostaglandin that grows hair and is the focus of pharmceutical drug development.
The work that our team has identified and focused on is a cellular enzyme function that is too often the impaired metabolic pathway, that when damaged by DHA in the diet, results in cellular lipid membrane lower cellular energy and lower cell oxygen production.
This has been accomplished by the hard work over decades and millions of dollars invested diving deeper than the studies that say that DHA is good for you - which has now been over-turned by newer science.
Our formulation physiologist together with our medical director who was the head of the Plastic Surgery department at MD Anderson in Texas, have decades understanding how the biochemistry of unadulterated Omega 6/3 nutritional oils in key proper ratios, and work to optimize cellular oxygen, and measureably improve artery plaque, shown by analyzing with Differential Pulse Wave Index (DPI).
Flawless Trillion™ GlamSnak™ functional oil blend has the optimized ratios, and sources, and formula as a Medical Food for patented, botanical-based lipids formulation is not duplicated by normal / typical dietary modification alone.:
1) Supports decreases in PGD2 and supports raising of PGE2 with the correct ratio of unadulterated nutritional fats—without side-effects that Minoxidil has such as excessive body hair growth - which is of course undesired because most people do not want more body hair.
2) Displaces the damage done to the cardiolipin membrane by fish oil DHA, which unleashes the energy production in the mitochrondria that was impaired and suffering while people didn't know what scientists have now discovered.
*E. Sullivan PhD et al
Journal Biological Chemistry 2018
"Docosahexaenoic acid (DHA) lowers cardiac mitochrondrial enzyme activity by replacing linoleic acid in the phospholipidome"
You may have read that Omega-6 acid can be bad - and it can be - if it is processed - which changes the biochemistry as warned about by Oxford Director of the University Laboratory of Human Nutrition, Hugh Sinclair in his 1956 letter published in The Lancet.
Fresh nuts and seeds and vegetables and eggs, and animals that have been fed grain will often carry a significant amount of unalterated oil with Omega-6 in their meat - that our ancient inland ancestors ate, are natural food sources of oil with Omega-6 in it, which makes up the healthy human cells wall and mitochrondria "energy-engine" membrane that utilizes oxygen for our cells.
You can't blame your doctor or nutritionist because they are not understanding how the scientific published articles got off track since the 1990's when articles about fish oil were increasingly published, with mistakes overlooking the biochemistry of what severely happens to the cardiolipin which is the fat membrane in the mitochrondria that is a major key to powering the cellular energy.
Skin tags develop from a deficiency of healthy fats.
Muscle lactic acid buildup post workout is correlated to less celluar oxygen metabolism, and the post-workout soreness becomes much less when the nutritional omega 6/3 unprocessed fats are at optimum functioning levels.
Q:
Can't I just eat certain foods?
A:
The ratio is essential because when the ratio is not accurate, more inflammation results.
Ancestral ratios in the diet were closer to between 2:1 to 5:1 Omega-6 to Omega-3, and it can be challenging to achieve without supplementation that covers the mandate of unprocessed and unaldterated requirements for the cells.
Other potential signs and symptoms of an unbalanced Omega-6 to Omega-3 ratio include:
- Joint pain or stiffness
- Fatigue
- Mood swings or irritability
- Difficulty sleeping
- Hair changes, such as dryness or hair thinning
- Artery plaque
- Blood vessel stiffness
- Impaired capillary circulation
- Dry eyes
Fish oil lowers mitochrondria enzyme function*, which is key to cellular oxygen and energy output, it has many studies that say it is anti-inflammatory, which it is, although the missing part of the understanding is that anti-inflammatory is not enough to justify taking it - when we now know that Prednisone is anti-inflammatory and yet we don't want it as our food - because it causes damage to the cells.
